Renal Function in Primary Aldosteronism

Renal function in primary aldosteronism.

Renal Function in Primary Aldosteronism To the Editor: We read the interesting article of Rossi et al1 investigating the involvement of the kidney in a large group of patients with primary aldosteronism (PA) who were recruited in a multicentric, Italian study. In these patients, the authors observed greater urinary albumin excretion (UAE) and higher prevalence of microalbuminuria than in essent...

Abnormalities of renal function and circulatory reflexes in primary aldosteronism.

IN PATIENTS with autonomic insufficiency, rapid intravenous infusion of an isotonic solution of sodium chloride results in abnormally rapid renal excretion of both sodium and water.' An identical renal response to intravenous infusion of saline solution was obtained in a preliminary study of two patients with primary aldosteronism.2 In subsequent investigations of hyperaldosteronism of renal an...

Coexisting renal artery stenosis and primary aldosteronism.

Effectiveness of eplerenone or spironolactone treatment in preserving renal function in primary aldosteronism.

OBJECTIVE Primary aldosteronism (PA) has deleterious effects on kidney function independent of blood pressure levels. Up to now, data on effectiveness of different PA therapies regarding renal function are scarce. DESIGN AND METHODS This prospective multi-center study included 29 patients with newly diagnosed PA evaluated before and 1 year after treatment initiation, and a second cohort inclu...

Unmasked chronic renal function deterioration after unilateral adrenalectomy in patients with primary aldosteronism

We report 2 cases of chronic estimated glomerular filtration rate (eGFR) decline after unilateral adrenalectomy due to primary aldosteronism. The patients were diagnosed with unilateral adrenal cortical adenoma releasing aldosterone. Two patients were examined for hypertension and hypokalemia. Unilateral laparoscopic adrenalectomy was performed in both cases, and pathology confirmed adrenal cor...